CPC in mouthwashes is shown in humans to break the membrane of SARS-CoV-2 and reduce the amount of active virus in saliva

Comunicació,


A clinical trial shows that rinsing the mouth for one minute with mouthwashes containing 0.07% Cetylpyridinium Chloride (CPC) reduces the number of infectious viruses in saliva such as SARS-CoV-2. A study led by the Fight Infections Foundation together with the IrsiCaixa AIDS Research Institute with the collaboration of DENTAID Research Center, a CataloniaBio  & HealthTech member.

This research, based on saliva samples from infected people seen in primary care centres, confirms the ability of CPC to break down the virus membrane. The study has demonstrated in vivo that SARS-CoV-2 loses its infectious capacity, as the destroyed membrane prevents it from penetrating cells. Therefore, mouthwashes  with 0.07% CPC could be an effective preventive tool against infection caused by the multiple variants of the coronavirus.

A recent report by the World Health Organisation (WHO) emphasises the important role that prevention and care of the oral cavity plays in good general health, and the close relationship with cardiovascular diseases and diabetes, among others. "The results of this study allow us to confirm that the clear relationship between the oral cavity and COVID-19, already demonstrated before, may also lead to a possible way to prevent its dissemination", concludes Dr Joan  Gispert, director of R&D&I at DENTAID.

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